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DrKkhan

survival study dtatistical tests

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What is the difference between log rank, cox proprtional hazard and mantel haenszel and when to use these three as a staistical test in survival studies??

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log rank test is univariate,non parametric, analysis the difference b/w survival curve of 2groups.

Cox proportional Hazard test semiparametric, assumes effects of multiple variable are contsant over a period of time.

example ;

Statistical analysis

Survival analysis using the Cox proportional hazard regression analysis with time-dependent variable was employed to examine the psychiatric predictors and baseline psychosocial predictors for substance use disorders. Psychiatric predictors included ADHD, conduct disorder, oppositional

defiant disorder, depressive disorders and anxiety disorders. Substance use disorders included misuse of and dependence on nicotine, alcohol, betel nut and illicit drugs. The outcome (survival time) was age at onset of the substance use disorder.

Psychiatric and psychosocial predictors of substance use disorders among adolescents Longitudinal study*

SUSAN S. F. GAU, MIAN-YOON CHONG, PINCHENG YANG,

CHENG-FANG YEN, KUNG-YEE LIANG and ANDREW T. A. CHENG (BJP 2007, 190:42-48 )

Mantel Haennszel Test - can be used to study the effects of two binary independent variables ( eg. male vs. female and treatment vs. placebo)

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