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mananiso

line of no effect

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in case of ODD RATIO how can we find line of noeffect to find out if the results are significant or not. they say 1 but sometimes the results given are 8 and they still say as it did not cross line of no effect :wacko: .

can any bodyhelp in interpreting this

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I'm not quite sure I understand your question... For odds ratios the line of no difference is always 1. This is because the odds ratio is calculate by dividing the odds of an event in the exposed group by the odds of an event in the control group. If there is no difference between the two groups then the odds of an event will be the same in both groups i.e. no difference so the odds ratio will be 1.

Odds ratios of greater than one indicate more events in the exposed group. Odds ratios of less than one indicate more events in the control group.

Whether or not the odds ratio is significant depends on the confidence intervals. If the confidence interval cross 1 then this is not significant.

An odds ratio of 8 may or may not cross the line of no difference, it depends on the CI.

OR 8 (CI 4.3-12.2) is significant as the CI do not cross the line of no difference.

OR 8 (CI 0.9-15.4) is not significant as the CI cross the line of no difference i.e the lower CI is <1

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yes,you got me right and thank you for the explanation

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Thank you I finally got it!

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Is there a problem with that :

OR 2.00, 95% CI = 1.48-2.70, p<0.0001

Thevconfidence interval embrace value of no difference or not ?

Are these values plausable or not ?

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Is there a problem with that :

OR 2.00, 95% CI = 1.48-2.70, p<0.0001

Thevconfidence interval embrace value of no difference or not ?

Are these values plausable or not ?

Plausible. Unless, I am missing the trick here. 

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