Gurpal

Feedback: MRCPsych Paper A - July 2015

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Please post your feedback about the MRCPsych Paper A exam. If you recall any questions, please post them.

 

Please refrain from discussing the answers to questions on this thread. Instead, start a new thread for each question. This makes for easier reading and makes it easier for future candidates to revise.

 

Good luck to everyone on results day.

 

:)

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Paper A2

Just to start discussion

I think make more sense now just having Genetics, Neuroscieance and pharmacology.

Seems lot of repeat questions from previous exam?

SSri with caution

Aripiracolr antagonist receptor

Few question alcohol/aldehyde/acetaldehyde question

Smoking effect

Will post more question later.

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Paper A (2)

 

What is 'copy number variation'

Male:female of pure frontal lobar degeneration

Which drug fast dissociation from D2 receptor

which condition has highest heritability  

Question of blood brain barrier - options were it is sole structural prevention, most drug cross by trans-membrane diffusion? 

EMI- Clinical feature and neuropathology of LBD, AD, Huntington's 

Question on lithium - EEG change in theraputic dose, whether it causes hypo/hypercalcaemia 

Partial agonists

In AD - Low AcH, Low serotonin/ low ach or low ach/ low glutaminae etc 

 

 

Please don't ask me about answers guys until the result is out. 

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Clozapine dissociates quickly from d2

Maybe autism has 90% heretibility

Lithium cased high calcium

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Hershl's Gyrus (which structure is bigger on right than left)

Blood supply to Corpus Callosum

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Blood supply to werneck's area

percentage of frontal lobes

Some thing about familial and sporadic Alzheimer's dementia

Gene involved in Down syndrome Alzheimer's dementia

Locus neurotransmitter

Emi

One clinical and one pathological finding in Lewy body and Alzheimer's dementia

tRNA

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Blood supply to corpus col is ant cerebral art

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Which drug binds to sigma receptor

What is the mechanism of flumazenil

7 year old boy with jerking movements repetitive behaviours

Aripiprazole is partial agonist/antagonist of dopamine (it didn't say receptor in the answer), d2 receptor, 5ht1

If a 1 in 100 risk of mother passing on to son.. What is the risk to have homozyg ?

Can't remember rest can anyone fill it in

Edited by kartgosu
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1:10000 for female

Aripip partial agonist

Boy had stereotypical movements

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Toll to stop translation was siRNA

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CAG gene on short arm of chromosome 4

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Precursor to Serotonin - L-Tryptophan

What results in protein production? - RNA translation

What is a noradrenaline and serotonin reuptake inhibitor? - duloxetine

What medical condition means a patient cannot be on MAOIs? - Phaeochromocytoma

What benzodiazepine has the longest half life in young adults?

Drug most likely to induce seizures? - Clozapine

Clozapine most likely adverse effect? - Cardiomyopathy, dry mouth, parkinsonism, NMS, diarrhoea, went for Cardiomyopathy

Alcohol addiction is related to which area of the brain? - Ventral tegmental

Which of the following is an NMDA receptor antagonist? - Memantine

Function of the amygdalae - options were overactivity in psychopathy, lesion in monkeys causes increased fear response, used in processing memory of emotional salience

Vascular origin of akinetic mutism presentation

3 separate questions on fucntion of disulfiram - aldehyde dehydrogenase inhibitor

Which is these is an example of aneuploidy? - Lost my head at this point, correct answer was Downs

Patient on risperidone has hyperprolactinaemia -

SSRIs effect on which receptor causes GI symptoms - 5HT3

Which antibiotic will cause facial flushing with alcohol? - Metronidazole, changed my answer at last minute due to panic onset to ciprofloxacin

Percentage risk of teratogenicity with sodium valproate?

What type of inheritance has mother passing to son?

EMI - Candiadate genes for schizophrenia - Neuregulin and Dysbindin, genes for Tau mutation

EMI - Patient on warfarin, needs an urgent INR due to taking which drug - st johns wort, Female patient, two drugs that inhibit oral contraceptive - st johns wort and carbemazepine

EMI - Antidpressant choices - 2 likely to cause weight gain, 1 used in atypical depression

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2 antidepressant red/increasing antipsychotics?

4 questions about tRNA, PUTS A STOP,BRIGE BETWEEN, ETC 

Effects of lithium, eeg, ecg?

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girl like to help her mother in kitchen,but burnt her hand in stove,now scared ,what learning?

stigma founder?

salle annae test-theory of mind

one emq about 'group process'

scape goating/bystader etc

Group conform

 

 

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Good student got rowdy in riots: conformity

Large group didnt help : bystanders

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Biculturalism

Hawthorne effect-example

university student-strie,broke the glass/court sentence- whic one is ?group polarisation

Attitude of ppl to stay in one thing ?complaince/cohesiveness

person remebers the phone number without writing it or rehearsal-what is it called

personality test ?minesota/thematic

 

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Jury being stern: deindividualization

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Remembering phone number : working memory

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Child doesn't remember how he learnt to ride a bike: procedural memory

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Ocd part of brain : orbitofrontal area

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group of people? cohesiveness /complaince

Ppl think their leader will do everythg for them ?autonomy/?dependency

 

EMQ-Eating disorder?hypekalemia

drinking water two similar ?which is hyponatremia and hyperglycemia

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burning hand in cooker?

 

Negative reinforcement.

 

Behaviour: avoid the cooker

 

Stimulus: Aversive stimulus of "burning hands" taken away.

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