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Gurpal

Feedback on the Part 2 ISQ/EMI papers Spring 2005

81 posts in this topic

After the Part II ISQ/EMI papers, please post an account of your experience, good or bad. If you remember any questions, please post them, even if you think you're repeating someone else's post. Thanks and good luck on results day!

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1. 5HT has both ion channel and ligand gated receptors

2.Delusions in depression predicts poor response to ECT

3.LSD causes psychedelic effects only after taking more than 25mg

4.LD is overrepresented in homicide offenders

5.Mean age of LD offenders are higher than that of normal people

6.XYY taller than average men

7. Angleman is caused by deletion of maternal chromosome at 15

8.Young adult with Downs likely to have fits

9.Autistic child is unable to make eye contact

10. There is more than chance association between Aspergers and GTS

11. About 2/3 of mothers with post natal depression has bonding problems with their children

12.CBT is effective in Rx of delusions

13..First rank symptoms predicts outcome of sch. after __years

14. LBD is charactersied by progressive deterioration of cognitive functions

15. Agnosia more suggestive of Alz than vascular dementia

16.Diencephalic amnesia has insight

17.Suicide rate in pathological gambling is around 40%

18.Childhood TLE is commonly associated with psychiatric disturbances

19.In BN cognitive therapy and interpersonal therapy are equally effective

20.Relapse rate of depression in elderly is significantly reduced by maintenance medication with TCA

Exact wording may not be correct ;)

EMI

1.

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1 v cjd is associated with triphasic waves in eeg in 80 % cases

2 cjd variant form is not seen in vegetarains

3 apraxia is more suggestive of picks than alzhiemers

4 disorganised attachment disorder is associated with non accidental injury

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5. Recency effect is preserved in organic amnesia

6 Retrograde amnesia is the best predictor of outcome in head injury

7 Minnesota recomendations are to reduce alcohol intake in dependence syndrome rather than abstain

8 impaired concentration is a poor predictor of response to ect in depression

9 amnestic confabulatory syndroem is associated with carbon monooxide poisoning

10 long standing multiple scleroses is commonly associated with cognitive decline

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11 persistent delusional disorder is typically seen with visual hallucinations

12 vitamin 12 deficiency commonly causes  dementia in elderly

13 lewy bodies seen in 40% of dementias

15 ist born child more commonly has alcohol problems

16 onset of schizophrenia is a predictor of outcome

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more q's which came in exam

17 rapid cycling mood disorder is more commonly seen in women

18 in panic disorder if ssris are discontinued less than 20 % people will relapse

19 sibling of autism has 8 % risk of dev autism

20 aspergers seen in 4:1 male to female ratio

21 stealing from shops is associated with anxiety disorder in children/ adolescents

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more

22 neuregulin1 gene associated with schizophrenia

23 myelin expressive genes associated with schizophrenia

24 deburetin ? gene linked with schizophrenia

24 proteomes are collection of expressed proteins

25 transcriptosomes are collection of m RNA's

26 gene is made of intron , exon , t rna

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hey still more

27 nmda receptor is a voltage sensitive calcium ion channel

28 ssri's coz sleep problems becoz they stimulate 5 ht2 receptors

29 clozapine dissociates from d2 rec slowly

30 benzos reduca deep sleep

31 caffeine antagonises benzos anxiolytic action

32 gaba bz recptor is likely to be reuced in brain of individuals with alochol dependence who are abstinent and neurologically normal

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33 phencyclidine produces its effect by blocking the ion channel of nmda ..or soemthing like that

34 lithium produces more effect on depression in bad than mania

35 atomoxetine has a half life of 24 hrs

36 doxazosin and reboxetinec an be given together

37 psychoanalytically oriented therapy has been shown to be effective in treating borderline disorder

38 orthopnea is likely to be associated with cardiac neurosis / effort syndrome

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39 imipramine causes loss of libido in 15 % people

40 masters n johnson use systematic desensitisation in fantasy routinely in treating sexual dysfunction

41 early cjd is assocaited with eeg changes

42 phobia n stimulus preparedness

43 trait neurotic implies non specific stimuli easily coz development of phobia

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39 confrontation of a person in precontemplation phase about his substance misuse MOST READILY brings about a change to action phase

40 sensitiver beziehungswahn is typically asociated with hallucinations

41 late onset schizophrenia is not associated with paranoid personality in early life

42 personality disorder people continue to show interpersonal difficulties in theIr life as they grow older

43 icd 10 is a dimensional classification

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44something on logistic regression being used for categorical variable

45 chi square of 5 by 3 table will have 15 df

46 regression done by least square method

47 day hospitals mange people with mod to mild dementia better than day centres significantly

48 child is likely to remember sexual abuse unless he is an infant

49 autistic children do not show attachment to mother

50 child who remembers sexual abuse after psychological therapy ..is likely to be telling full truth....somethign like that

51 measurement scales with multiple answers increase reliability in measuring attitude

52 semantic differential scale is ised in attiutde measurement

53 semantic demntia is seen becoz of fronto temporal lobe atrophy

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54 sleepwalking can be provoked by alcohol

55 nightmares are associated with nocturnal enuresis frequently

56 nightterror are associated /recognised in depression

57 narcolepsy with cataplexy is seen in 3 per 10 000 people

58 10 percent of alzheimers dis is becoz of mutation of APP

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59 encopresis is ass with enuresis

60 enuresis has genetic locus hetrogeneity

ok gotts sleep now...tired.. more q later

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EMI's for Basic Science Paper

EEg in Old Age

choice of triphasic wave

spikes

posteriorly conserved alpha?

theta?

beta?

chose one two three of the following for clinical scenario?

1old man depressed for some time developing cognitive deficit

2old man whose wife died etc etc???

3???

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EMI 2 Basic Sciences

chose neuro anatomy most related

mammilary bodies

superior colliculi

olivary nucleus

lentiform nucleus

arcuate fasciculus

temporal pole

subiculum

uncinate ...

1 man with alcohol problems

2 auditory difficulties

3 ???

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EMI 3 Validity

a a sister screening for depression on ward selects 8 people with depression out of a total of nine who have depression

b a sister screening for depression on a ward selects 80 people who haven't got depression out of a total of 100 who havn't got depression

c we usually choose diagnostic categories from ICD 10

d concordance in diagnosis between GHQ and Becks depression inventory

e 95 % of people diagnosed with LBD screened with test x?? have Lewy Body Dementia

f the sister in a and b checks her figures na dfinds a total of 8 people with depression test positive from a total of 28 with depression on the ward

g some Alzhemers test that is very reliable for AD??

1Construct Validity

2C....... Validity

3Discriminatory Validity

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EMI Basic Sciences 4

Genetic Disorders

1 self harm in boy with self biting- Lesch Nyan

2 Obsessional eating -Prader Willi

3 6 year old girl with handwringing???

other choices

Rett's

and lots of other wierd ones

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EMI Basic Sciences 5

oh yes!!!

the worst question of them all

radioligands and different imaging modalities

really unusuall ligands

fmri

volumetric mri

t1 weighted MRI

in which research scenario would each one be best employed???

ie measuring neuronal loss in anterior cingulate??

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EMI clinical1

Drugs of abuse linked to clinical presentations

list of amphetamine

ketamine

caffeine

alcohol

cocaine

phencyclidine

mushrooms

volatile gases

1 young guy at a party mild respiratory depression dilated pupils and ?hypotension

2young guy experiencing bad trip dilated pupils tachcardic, sweating,

3 young guy derpressed past 3 months dilated pupils, some muscle stiffness

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EMI Clinical 2

Drugs adverse effects

lithium toxicity

nms

serotonin syndrome

diabetes insipidus

diabetes mellitus

cardiomyopathy

+ others

1on clozapine, palpitations, tachycardia, breathless

2 on lithium polydipsia, polyuria, lethargy high Na levels

3 on olanzapine, muscle rigidity

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EMI Clin 3

Defence Mechanisms Linked to clinical story

Denial

Idealisation

Projective Identification

Reaction Formation

Sublimation

Splitting

+others

1 patient taken large overdose and admitted. wants to discharge herself. doctor feeling anxious about discharging her, patient now seems better

2 patient tells of how good his childhood was when we know from notes he was taken into care because neglected by mother

3 patient telling team member that he is great, a week later putting in a complaint for no apparent reason

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Clin EMI 4

Child Psych

Logotherapy

Parent training

Family Therapy

Methylphenidate

Lithium

+ others

1 4 year old taking the piss at school wit teachers and not respecting his mother at home

2 17 year old agrressive to the point parents have court injunction against him, he is aggressive in all circumstances but no other symptoms

3 13 year old girl aggressive, trouble at school, diagnosed as hyperkinetic by a psychologist

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Clin EMI 5

sorry, can't remeber this one!!lost it, its been a long day

good luck all for the autumn exam!

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Proteomes…… proteins…….cell

Transcriptoms collections mrna

Leukariosis gait disturbance

Benzodiazepine withdrawl perception hyper

Disulram associated with mania

Atamoxitine is a noradrenaline uptake inhibitor

Half life of atamoxitine is 24 hours

Disulphram and acamprosate interact

Fluoxetine increases clozapine levels

In a 8 year old boy with primary nocturnal eneuresis, with no other urinary or psychiatric symptoms, iq testing is indicated

Heritability of conduct disorder 0.1 – 0.2 %

Adhd is associated with alcohol dependence

Lofexidine is an alfa agonist

Phencyclidine blocks the nmda receptor

Logistigal regression… least squares meathod

Prevalence of moderate and severe learning difficulty (iq<50) 3 in 1000

Vegetarians do not get new variant cjd

Encoporesis is associated with parenting style

Encoporesis is associated with primary eneuresis

Icd 10 is dimentional

Huntingtons is caused by a cag repeat of greater than 35 in most cases

Naltrexone can be used for self mutilating behaviour

Autism is associated with a lack of imaginative play

Caseness… index…present state examination…..research

Homosexuals use more drugs and alcohol

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