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Guest khuram

to be decided!!

19 posts in this topic

A higher physical dep in pt

B living in instituition

C living with another person

D male carer

E male patient

F poor previous relationship

G carer married to pateitn

H patient has dementia

1 give 2 risk factors for elder abuse---poor previous relationship,living in instituition

2 give 3 risk factors for carer distress---patient has dementia,higher physical dep in pt,male patient

3 give 3 factors that will reduce depression in carers of elderly --carer married to pateitn,living with another person,higher physical dep in pt

(not all are correct – there were definitely 3 weird PET and 1 SPECT with tracers no-one had ever heard of)

flurodeoxyglucose PET

flumazenil PET

oxygen5 PET

123I Iomazenil SPECT

fMRI spectroscopy

volumetric MRI

t1 weighted MRI

Select the appropriate tests for the following research scenarios

1 2 tests for measuring neuronal loss in frontal lobe

2 2 tests for total brain volume loss

3 1 test for neuronal loss

A sister screening for depression on ward selects 8 people with depression out of a total of nine who have depression

A sister screening for depression on a ward selects 80 people who haven't got depression out of a total of 100 who haven't got depression

We usually choose diagnostic categories from ICD 10

Concordance in diagnosis between GHQ and Becks depression inventory

95 % of people diagnosed with LBD screened with test x?? have Lewy Body Dementia

The sister in a and b checks her figures and finds a total of 8 people with depression test positive from a total of 28 with depression on the ward

Some Alzheimers test that is very reliable for AD??

1 Give 3 examples of Construct Validity

2 Give 2 examples of Concurrent Validity

3 Give 1 example of Discriminatory Validity

Normal EEG

Triphasic wave

Spikes & waves

Generalised slowing with preserved posterior alpha waves

Increased theta

Decreased beta

Select two or three of the above for the clinical scenario

1 A 70 year old man, depressed for some time who has recently become aggressive and shoplifting (2)

2 A 65 year old man whose wife died has died recently and he has become convinced he has cancer (2)

3 A 63 year old woman with 9 month history of memory loss and a recent fall (3)

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this is a good idea khuram... i'll restrain for a bit... not that i know the answers anyway though....

the one with the radio ligands definitely something wrong with it... most of those u can't even google...!!!!

lets wait and see :-?

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A higher physical dep in pt

B living in instituition

C living with another person

D male carer

E male patient

F poor previous relationship

G carer married to pateitn

H patient has dementia

1 give 2 risk factors for elder abuse---poor previous relationship,living in instituition

2 give 3 risk factors for carer distress---patient has dementia,higher physical dep in pt,male patient

3 give 3 factors that will reduce depression in carers of elderly --carer married to pateitn,living with another person,higher physical dep in pt

1. poor previous relationship and carer married to patient (ref Manchester notes)

2. dementia, male patient, poor previous relationship ( seminar series)

3. male carer, living with another person, higher physical dependence

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:)

1. Deletions on chromosome gamma2

2. APP mutations

3. APO E4 polymorphism

4. Huntington's mutations

5. No genetic test

6. Presenilin (-1 or -2)

7. Tau mutations

8. Trisomy 21

9. Werner's gene mutation

QUESTIONS:

1. 60yr old male, history of dementia, recent disinhibited behaviour. has parkinsonism. (choose 1)

2. 50yr old male, slowly progressive dementia. mother and an uncle on mother's side have similar disease (choose 2)

3. 40yr old, atypical psychiatric disorder, dad had chorea without any psychiatric disorder at age 60 (choose 1)

A) ApoE

B) APP

C) Presenilin

D) Huntington gene

E) No genetic test

50-year-old diagnosis with dementia. mother and 2 maternal uncle has similar condition (choose 1)

Dementia with chorea (choose 1)

Parkinson disease (choose 1)

A) Hyperglycemia

B) Hypoglycemia

C) Hyponatremia

D) Hyperthyroidism

E) Hyperkalemia

F) Hypercalecemia

1. Alcoholism, after binge-drinking, anxious and confused in A&E (choose 1)

2. Depressed middle age gentleman complained of lethargy, nausea, muscle cramp. Recently started on paroxetine (choose 1)

3. Schizophrenic patient on clozapine complained of abdominal pain and confusion (choose 1)

Hippocampus sclerosis

Enlarged ventricle

Enlarged ventricle

Macrocephaly

Cortical Lewy Body

Cerebellar damage

Enlarged lentifrom

1. TLE (choose 1)

2. After drug treatment in schizophrenia (choose 1)

3. Autism (choose 1)

P450 enzyme induction

Effect on striatal D2 receptor

Effect on meso-limbic D2 receptor

Effect on 5HT2 receptor

Effect on 5HT3 receptor

1. Started St John’s wort and later pregnant despite taking OC pill (choose 1)

2. On antipsychotic and develop EPSE (choose 1)

3. On fluoxetine, started on Li and became confused (picture of serotonin syndrome). (choose 1)

A) Citalopram

B) Despiramine

C) Escitalopram

D) Fluoxetine

E) Reboxetine

F) Quetiapine

G) Sertraline

H) Risperidone

1. 11 year old developed OCD for 6 months and later depressed mood. (choose 1)

2. OCD teacher with sexual obsessions, unlikely to have that antidepressant drug (choose 2)

3. OCD child with SSRI for some time but still OC with motor tics. (choose 2)

A) Chi-square test

B) McNemar test

C) Fisher test

D) Cluster analysis

E) ANCOVA

F) ANVONA

G) Multiple regression

1. Demonstrate association of height (parametric) and ASPD (choose 3)

2. Relation of conduct disorder and ASPD (choose 2)

3. ASPD vs height and IQ (height and IQ correlated) (choose 2)

A) Flupentixol depot

B) Risperidone

C) Olanzapine

D) Clozapine

E) Quetiapine

F) Haloperidol

1. Older schizophrenic women, DM, agreed to take medication but irregular compliance and psychotic. When son reminded her, end up in a quarrel.

2. Psychotic elderly man, persistent psychotic symptoms, not tolerating oral flupentixol. Not responding to sulpiride and olanzapine.

3. Case of Parkinson’s disease. Not on anti-PD drug and antipsychotic naïve. Distressed by VH.

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hi LS can u explain why the particular choices are right...

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TESTS YOU WOULD USE TO CONFIRM THE DIAGNOSIS OF  THE CONDITIONS

Deletions on chromosome gamma2  

2. APP mutations  

3. APO E4 polymorphism  

4. Huntington's mutations  

5. No genetic test  

6. Presenilin (-1 or -2)  

7. Tau mutations  

8. Trisomy 21  

9. Werner's gene mutation  

10 .PARKINS GENE

QUESTIONS:  

1. 60yr old male, history of dementia, recent disinhibited behaviour. has parkinsonism. (choose 1) NO GENETIC TEST

I DONT THINK WE YET DO ANY GENETIC TEST TO CONFIRM TEH DIAGNOSIS OF PARKINSONS

2. 50yr old male, slowly progressive dementia. mother and an uncle on mother's side have similar disease (choose 2)  APP AND PRESEN 1 , 2

3. 40yr old, atypical psychiatric disorder, dad had chorea without any psychiatric disorder at age 60 HUNTINGTONS MUTATION

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) Hyperglycemia  

B) Hypoglycemia  

C) Hyponatremia  

D) Hyperthyroidism  

E) Hyperkalemia  

F) Hypercalecemia  

1. Alcoholism, after binge-drinking, anxious and confused in A&E (choose 1)  HYPOGLYCEMIA

2. Depressed middle age gentleman complained of lethargy, nausea, muscle cramp. Recently started on paroxetine (choose 1)  HYPONATREMIA

3. Schizophrenic patient on clozapine complained of abdominal pain and confusion (choose 1)  HYPERGLYCEMIA

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Hey khuram, thanks ;)

lets get on before its too late!!!

P450 enzyme induction  

Effect on striatal D2 receptor  

Effect on meso-limbic D2 receptor  

Effect on 5HT2 receptor  

Effect on 5HT3 receptor  

1. Started St John’s wort and later pregnant despite taking OC pill P450 enzyme induction  (choose 1)  

2. On antipsychotic and develop EPSE Effect on striatal D2 receptor  (choose 1)  

3. On fluoxetine, started on Li and became confused Effect on 5HT2 receptor  (picture of serotonin syndrome). (choose 1)  

Although i thought serotonin sy had something to do with alpha receptors????

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A) Hyperglycemia  

B) Hypoglycemia  

C) Hyponatremia  

D) Hyperthyroidism  

E) Hyperkalemia  

F) Hypercalecemia  

1. Alcoholism, after binge-drinking, anxious and confused in A&E HYPOglycaemia(choose 1)  

2. Depressed middle age gentleman complained of lethargy, nausea, muscle cramp. Recently started on paroxetine HYPOnataemia(choose 1)  

3. Schizophrenic patient on clozapine complained of abdominal pain and confusion ?Hyper calcaemia?? Yeppp i agree Hyperglycaemia.. and sorry hadnt realise u had already posted :-[(choose 1)  

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A) Chi-square test  

B) McNemar test  

C) Fisher test  

D) Cluster analysis  

E) ANCOVA  

F) ANVONA  

G) Multiple regression  

1. Demonstrate association of height (parametric) and ASPD (choose 3)  

chi squares, ancova, ??multiple regression

2. Relation of conduct disorder and ASPD (choose 2)

McNEMAR - I think should be categorical and paired data!

 

3. ASPD vs height and IQ (height and IQ correlated)

multiple regression MANOVA - i'm assuming typo right???(choose 2)  

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CPIED form EUREKA:

1. 60yr old male, history of dementia, recent disinhibited behaviour. has parkinsonism. (choose 1) NO GENETIC TEST

I DONT THINK WE YET DO ANY GENETIC TEST TO CONFIRM TEH DIAGNOSIS OF PARKINSONS

It could be frontotemporal dementia, in which case TAU MUTATIONS, maybe ok :-?

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THIS IS DIFFCULT

) Chi-square test  

B) McNemar test  

C) Fisher test  

D) Cluster analysis  

E) ANCOVA  

F) ANVONA  

G) Multiple regression  

1. Demonstrate association of height (parametric) and ASPD WOULD BE CATEGORICAL DATA ...IE EITHER U HAVE ASPD OR U DONT HAVE A DIAGNOSIS OF ASPD...

actually aspd can be taken as a parametric data...severity of aspd then it will be continuous data

(choose 3)  

2. Relation of conduct disorder and ASPD 2 CATEGORICAL DATAS(choose 2)  SO A AND B

can b etwo continuous data if comparing severity of aspd and conduct disorder

3. ASPD vs height and IQ (height and IQ correlated)

CATEGORICAL DATA  OR DEPENDENT VARIABLE WITH 2 PARAMETRIC INDEPENDENT VARIABLES(choose 2)  

aspd can be considered as cont sdata as well....

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A higher physical dep in pt

B living in instituition

C living with another person

D male carer

E male patient

F poor previous relationship

G carer married to pateitn

H patient has dementia

1 give 2 risk factors for elder abuse---poor previous relationship,living in instituition

2 give 3 risk factors for carer distress---patient has dementia,higher physical dep in pt,male patient

3 give 3 factors that will reduce depression in carers of elderly --carer married to pateitn,living with another person,higher physical dep in pt

1. poor previous relationship and carer married to patient (ref Manchester notes)

2. dementia, male patient, poor previous relationship ( seminar series)

3. male carer, living with another person, higher physical dependence

For the 1st one, i would go for dementia (instead of living in institution) as dementia is an independant factor for abuse from both prof carers and family - although contradicting Manchester notes!!!!

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A) Flupentixol depot

B) Risperidone

C) Olanzapine

D) Clozapine

E) Quetiapine

F) Haloperidol

1. Older schizophrenic women, DM, agreed to take medication but irregular compliance and psychotic. When son reminded her, end up in a quarrel.

Flupentixol depot

2. Psychotic elderly man, persistent psychotic symptoms, not tolerating oral flupentixol. Not responding to sulpiride and olanzapine.

D) Clozapine

3. Case of Parkinson’s disease. Not on anti-PD drug and antipsychotic naïve. Distressed by VH.

Quetiapine (???)

:-? :P

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A) Citalopram

B) Despiramine

C) Escitalopram

D) Fluoxetine

E) Reboxetine

F) Quetiapine

G) Sertraline

H) Risperidone

1. 11 year old developed OCD for 6 months and later depressed mood. (choose 1) Fluoxetine

2. OCD teacher with sexual obsessions, unlikely to have that antidepressant drug (choose 2) ????

3. OCD child with SSRI for some time but still OC with motor tics. (choose 2) Risperidone,.... :P

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A) Flupentixol depot  

B) Risperidone  

C) Olanzapine  

D) Clozapine  

E) Quetiapine  

F) Haloperidol  

1. Older schizophrenic women, DM, agreed to take medication but irregular compliance and psychotic. When son reminded her, end up in a quarrel.  

Flupentixol depot  

2. Psychotic elderly man, persistent psychotic symptoms, not tolerating oral flupentixol. Not responding to sulpiride and olanzapine.  

D) Clozapine  

3. Case of Parkinson’s disease. Not on anti-PD drug and antipsychotic naïve. Distressed by VH.  

Quetiapine (???)

:-? :P

all answers correct. your choice for no 3 is the correct answer.

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A) Citalopram  

B) Despiramine  

C) Escitalopram  

D) Fluoxetine  

E) Reboxetine  

F) Quetiapine  

G) Sertraline  

H) Risperidone  

1. 11 year old developed OCD for 6 months and later depressed mood. (choose 1)  Fluoxetine  

2. OCD teacher with sexual obsessions, unlikely to have that antidepressant drug (choose 2)  ????

3. OCD child with SSRI for some time but still OC with motor tics. (choose 2)  Risperidone,.... :P

1. 11 year old developed OCD for 6 months and later depressed mood. (choose 1) Sertraline.

no antidepressant is licensed for child and adolescence officially but the only exception is Sertraline fully licensed for OCD.

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hey olu,

i thought nice were saying if OCD and depression, then to precribe fluoxetine..

Waht about the other 2 anyway??

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