Go on then!!!!!!!!

[Guest khuram]

in Alzheimers disease there is decreased latency in the evoled responses in EEG

presence of birth injury affects the age of onset of SCZ

Polymerase chain reaction requires thermostable DNA polymerase

Sleep deprivation reduces the number of killer cells in the brain

Munchausun by proxy is classified as a factitious disorder in the ICD-10

MTHFR gene is a risk for hyperchromocysteinaemia

Men have a greater prepulse inhibition than females.

MDMA causes physical dependance

amphetamine causes physical dependance

ecstasy is associated with a withdrawl state

Conduct disorder has 0.1-0.2 inheritance ----- >

patints with MS who complain of fatigue are usually depressed

Imperforate anus at birth suggests Down's syndrome

Memory problems improve towards the end of a course of ECT

Delirium is associated with theta waves in EEG

appettitive conditioing can exacerbate avoidance

The genetic risk for Schizophrenia and BPAD are associated with differences in patterns of grey matter volume deficits on MRI

[Carlo 0]

Polymerase chain reaction requires thermostable DNA polymerase

TRUE

Sleep deprivation reduces the number of killer cells in the brain

FALSE

See previous entries

[Carlo 0]

The genetic risk for Schizophrenia and BPAD are associated with differences in patterns of grey matter volume deficits on MRI

TRUE

I corrected a recent entry of mine saying false - Pubmed search

[Carlo 0]

Men have a greater prepulse inhibition than females.

FALSE

6: Ludewig K, Ludewig S, Seitz A, Obrist M, Geyer MA, Vollenweider FX.

The acoustic startle reflex and its modulation: effects of age and gender in humans.

Biol Psychol. 2003 Jul;63(3):311-23.

Seventeen males and 16 female participants were tested three times at monthly intervals. Aged participants showed significantly lower startle magnitude and significantly more habituation than younger participants, but there was no effect of age on PPI or prepulse facilitation. Moreover, there were[highlight] no effects of gender on startle magnitude, PPI, prepulse facilitation, or habituation measures.[/highlight] Healthy males and females exhibited stable startle magnitudes and PPI across sessions. The results demonstrated that PPI and startle are reliable measures of sensory information processing in both genders and that startle magnitude and habituation are age-dependent measures.

[Carlo 0]

Conduct disorder has 0.1-0.2 inheritance (you mean heritability, I guess)

FALSE

J Child Psychol Psychiatry. 2005 Jun;46(6):580

Genetic and environmental influences on conduct disorder: symptom, domain and full-scale analyses.

Gelhorn HL, Stallings MC, Young SE, Corley RP, Rhee SH, Hewitt JK.

Heritability estimates were .49, .55 and .53 for the aggressive domain, non-aggressive domain, and full-scales, respectively.

[ABOBUTTA 0]

Munchausun by proxy is classified as a factitious disorder in the ICD-10 ..FALSE

ICD10 F68.1 the exclusin criteria

[ABOBUTTA 0]

Memory problems improve towards the end of a course of ECT

Delirium is associated with theta waves in EEG

both False some where in this site :-/

[Carlo 0]

Memory problems improve towards the end of a course of ECT  

Delirium is associated with theta waves in EEG

both False some where in this site :-/

Sure FALSE

First just makes clinical sense to me

Second one:

Delirium usually shows slow alpha activity and increased delta activity on EEG.

http://www.fleshandbones.com/physiology/davies/box.cfm?ISBN=0443045593&SetID=9&BoxID=97

[michaelshamrock 0]

yeah carlo delirium= d= delta thats how i remember it

alpha = a = ageing lol

[michaelshamrock 0]

Men have a greater prepulse inhibition than females.

FALSE

this is correct but beware female schizo patients hold true

[Carlo 0]

Imperforate anus at birth suggests Down's syndrome

I'd go FALSE: IA is indeed a feature of DS, but having it doesn't necesserily mean youo got DS

It occurs in 1:5000 live birhts.

[Carlo 0]

Oh, Hi Mich.. thanks for that..

Just trying to keep energies going.

Last one not answered in this thred:

presence of birth injury affects the age of onset of SCZ

TRUE

Replicated finding - f.e.

1: Schizophr Bull. 2000;26(2):351-66. Related Articles, Links

A prospective cohort study of genetic and perinatal influences in the etiology of schizophrenia.

Cannon TD, Rosso IM, Hollister JM, Bearden CE, Sanchez LE, Hadley T.

We found that the odds of schizophrenia increased linearly with increasing number of hypoxia-associated OCs and that this effect was specific to cases with an early age at onset/first treatment contact.

[Guest khuram]

come on, come on.....

Shoplifting is associated with bulimia nervosa

Anorexia nervosa of later onset has higher mortality..... than that of earlier onset.

Feeling muddled is a common symptom of post-pregnancy blues .

Bulimia is associated with increased mortality

In treatment of anorexic patients with severe weight loss, initial weight gain is associated by cognitive improvement

The effect of cortisol is more than that of DHEA in adolescent depression

Leukoariosis in old age is seen in anxiety and depression

Dexamethasone non-suppression can be diagnostic of depression

The differences in scores between BDI and HAM-D are due to the way they are conducted

Use of a light box for Seasonal Affective Disorder is equally effective when used in the morning or the evening

Imipramine and ECT work synergistically.

First onset of depression in a man aged 65 without any previous history of depression is likely to be dementia

Visual hallucinations are a common feature of depressive psychosis in the elderly

In the elderly, relapse of depression is more likely following ECT than using tricyclic antidepressants

MAOIs reduce the efficacy of oral hypoglycemic drugs

The UK National Psychiatric Morbidity data shows that no more than 2% of adults have a psychiatric illness.

The UK National Psychiatric Morbidity data shows that the increased prevalence of depression and Generalised Anxiety Disorder (GAD) in urban areas is not due to unemployment

Carbon monoxide poisoning rarely causes permanent cognitive impairment

Reducing the availability of means of suicide does not stop suicides in long term

Divorce is a recognized cause of PTSD

Atypical facial pain characteristically presents as a deep facial pain

in simple phobias, rituals are common

Severe anxiety may lead to delirium

Generalised anxiety disorder is called 'nervous shock' in law.

Thought blocking effectively treats obsessions

Anxiety disorders in elderly almost always have onset in earlier life

Shoplifting is more common in OCD

Cocaine use is associated with somatisation

Perinatal birth injury brings forward the onset of schizophrenia

There is a 5% chance of bipolar homozygous twins developing schizophrenia

Orbitofrontal circuits are affected in schizophrenia

Late paraphrenia is found in more than 10% of old people

5% of elderly schizophrenics have a first degree relative with schizophrenia

The combination of a calcium channel blocker and dopamine agonist is used to treat neuroleptic malignant syndrome.

Delusional disorder of old age (paraphrenia) usually progresses to dementia

Presence of birth injury affects the age of onset of schizophrenia

Narcolepsy is associated with loss of muscle tone in clear consciousness

Nocturnal enuresis present in all parts of sleep

Chronic Factitious disorder is also known as Munchausen syndrome

An young adult with Downs Syndrome is likely to have epilepsy

[dharma 0]

Thanks khuram... gets us out of the tedium!!

Shoplifting is associated with bulimia nervosa

TRUE - poor impulse control

Anorexia nervosa of later onset has higher mortality..... than that of earlier onset. TRUE one of the poor prognostic factors

Feeling muddled is a common symptom of post-pregnancy blues .

FALSE - this is mpre to do with post natal depression and pn psychosis

Bulimia is associated with increased mortality

FALSE ?? tricky one, i think it is false true for anorexia though

In treatment of anorexic patients with severe weight loss, initial weight gain is associated by cognitive improvement

grrrrrr can someone answer thissss and confrim the one above!!

The effect of cortisol is more than that of DHEA in adolescent depression

YRUe increase cortisol to dhea ratio

Leukoariosis in old age is seen in anxiety and depression TRUE

Dexamethasone non-suppression can be diagnostic of depression

bllll 60% have it would be a poor test coz lots of non depressed people also have this.

FALSE

The differences in scores between BDI and HAM-D are due to the way they are conducted

FALSE - ok one is self and the other oserver marked... but they are just 2 completely different schedules, with diff questions, different vaalidity reliability..... anyone :-[

Use of a light box for Seasonal Affective Disorder is equally effective when used in the morning or the evening

FALSE - better in the morning manchester

Imipramine and ECT work synergistically.

??False

First onset of depression in a man aged 65 without any previous history of depression is likely to be dementia

??... I would say false - only 5% of people of 65 have demetia, and actually between 10 - 13% have depression... my maths

Visual hallucinations are a common feature of depressive psychosis in the elderly

FALSE

In the elderly, relapse of depression is more likely following ECT than using tricyclic antidepressants

TRUE

MAOIs reduce the efficacy of oral hypoglycemic drugs

FALSE ??? cant find my ref... and now doubting myself please confirm

The UK National Psychiatric Morbidity data shows that no more than 2% of adults have a psychiatric illness.

FALSE

The UK National Psychiatric Morbidity data shows that the increased prevalence of depression and Generalised Anxiety Disorder (GAD) in urban areas is not due to unemployment

???

Carbon monoxide poisoning rarely causes permanent cognitive impairment

???

Reducing the availability of means of suicide does not stop suicides in long term

contentious... I am sure the phrasing of this is wrong. my answer for my interpretation of the above is TRUe. by decreasing availability of means, u can reduce the prevalence of suicide and there fore stop quite a substatial nr of suicides from occurring

Divorce is a recognized cause of PTSD

FALSE

Atypical facial pain characteristically presents as a deep facial pain

TURE

in simple phobias, rituals are common

FALSE - avoidance behaviour, not rituals

Severe anxiety may lead to delirium

GRRRRRR sort tis out before WEd please

Generalised anxiety disorder is called 'nervous shock' in law.

FALSE

Thought blocking effectively treats obsessions

FASLE - cognitive avoidance wil only exacerbate the problem

Anxiety disorders in elderly almost always have onset in earlier life

TRUE

Shoplifting is more common in OCD

FALSE

Cocaine use is associated with somatisation

MY anser is going to be FALSE - havent been able to find any evidence to substatiate the contrary - crikey i am turning into a pedantic aspergerry sort - when is this over please do i can be normal again

Perinatal birth injury brings forward the onset of schizophrenia

TRUE

There is a 5% chance of bipolar homozygous twins developing schizophrenia

FALSE 45%

Orbitofrontal circuits are affected in schizophrenia

FALSE

Late paraphrenia is found in more than 10% of old people FASLE

although it is 10% of th elderly psych admissions

5% of elderly schizophrenics have a first degree relative with schizophrenia

FALSE

The combination of a calcium channel blocker and dopamine agonist is used to treat neuroleptic malignant syndrome.

TRUR dantrolene and bromocriptine for example

Delusional disorder of old age (paraphrenia) usually progresses to dementia

FALSE

Presence of birth injury affects the age of onset of schizophrenia

TRUR brings it forward heard murray talking about this also low iq

Narcolepsy is associated with loss of muscle tone in clear consciousness

FALSE - cataplexy and even if so, they lose muscle tone and fall deeply asleep isnt it... clarify please

Nocturnal enuresis present in all parts of sleep

TURE

Chronic Factitious disorder is also known as Munchausen syndrome

?? - not if it was by proxy... but this is a different q

An young adult with Downs Syndrome is likely to have epilepsy

???

;)if u can help pls with :-

[dharma 0]

What about these 2:

1. tourettes has more than chance association with aspergers

2. Specific reading disorder have lower perfomance than verbal intelligence scores

[dharma 0]

some few more still, sorry if any of them are reapeats.. just clarify:

1. the QT interval is independant of the heart rate

2. visual hallucinations are a recognised feature of cannbis use

3. in panic disorder is treated with ssri, there is 40% recurrencerate on stopping meds

4. managing enmeshment is part of contingence therapy

5. insulin release by the pancreas reduces tyrosin/tryptophan

6.the impact of life events (revised) scale has a measurement for increased arousal

7. T4 levels are raised in anorexia

8. after gradual reduction of antipsychotics in LD, further medication is usually needed

9. tau protein interferes with microtubules formation

10 pindolol blocks pre and post synaptic 5ht receptors

11. having a seizure is moe suggestive of picks than alzheimers

12. motivational interviewing aims to reduce primary gain

13 perinatal complication is risk factor for bipolar

14 autistic adolescents have higher incidence of fits

8-)

[dharma 0]

more...

(don't forget the 2 q, 2 posts up... bugging me)

1. sibling of autism has 8% chance of developing autism

2. narcolepsy with cataplexy is seen in 3 per 10,000

3.disulfuram and acamprosate interact

4. hyperphosphorilation of tau leads to formation of tangles in alzheimers

5. 40 - 70% of cases of tuberous sclerosis have ld

6. an acute confusional state can persist 3 weeks after co poisoning

7. lithium can cause peripheral neuritis

[michaelshamrock 0]

more...

(don't forget the 2 q, 2 posts up... bugging me)

1. sibling of autism has 8% chance of developing autism

2. narcolepsy with cataplexy is seen in 3 per 10,000 true

3.disulfuram and acamprosate interact f

4. hyperphosphorilation of tau leads to formation of tangles in alzheimers true

5. 40 - 70% of cases of tuberous sclerosis have ld

6. an acute confusional state can persist 3 weeks  after co poisoning t

7. lithium can cause peripheral neuritis f

[dharma 0]

[smiley=2vrolijk_08.gif] [smiley=lolk.gif] [smiley=dankk2.gif] [smiley=angry.gif]

u little :evil:

but u dont have to do this, y'know[smiley=happy.gif]

:-*

[drkukkadapu 0]

Men have a greater prepulse inhibition than females.

true

Sex effects in prepulse inhibition and facilitation of the acoustic startle response: implications for pharmacological and treatment studies

Ingrid Aasen

Department of Psychology, Division of Psychological Medicine, Institute of Psychiatry, London, UK, i.aasen@iop.kcl.ac.uk

Lavanya Kolli

Department of Psychology, Institute of Psychiatry, London, UK

Veena Kumari

Department of Psychology, Psychological Medicine, Institute of Psychiatry, London, UK

Journal of Psychopharmacology, Vol. 19, No. 1, 39-45 (2005)

DOI: 10.1177/0269881105048890

© 2005 British Association for Psychopharmacology

Prepulse inhibition (PPI) refers to the reduction in the response amplitude to a startling stimuli (pulse) if it is preceded (i.e. 30-500 ms) by a weak stimulus (prepulse). If the time interval between the prepulse and pulse is more than 500 ms, then an increase in this response amplitude can be seen, termed prepulse facilitation (PPF). PPI is thought to represent an operational index of sensorimotor function whereas PPF is thought to reflect, at least to some degree, sustained attention. Interestingly, PPI is found to be sexually dimorphic, with men exhibiting more PPI than women when subjects are tested without regard to where they are in the menstrual cycle, and to be impaired in several neuropsychiatric disorders known to exhibit sex differences in their clinical presentation. PPF has received relatively less attention in both normal and clinical studies. This study examined sex differences in both PPI and PPF in 62 healthy subjects (34 women, 28 men) using a range of prepulse-to-pulse intervals to elicit PPI (30, 60, 120, 240 and 480 ms) and PPF (1000 and 2000 ms). Men showed higher PPI than women but women showed higher PPF compared to men. These results suggest that reduced PPI in healthy women is not a simple reduction but rather a shift of the inhibition/facilitation curve in the direction of facilitation in women, relative to men. Future studies investigating pharmacological and treatment effects using a prepulse modification paradigm in normal and clinical populations of both sexes would benefit from an examination of sex effects and assessments of both PPI and PPF.