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slartibartfast

The EEG thread

2 posts in this topic

Petit mal epilepsy classically has a 3 Hz spike and wave pattern.

Grand mal epilepsy is identified by large 8-12 Hz spikes in groups during tonic-clonic seizures.

Migraine can be difficult to distinguish from cerebrovascular disease, especially if the presentation is with acute hemiplegia. The EEG in these migraine sufferers shows localized slow wave activity. Generally in migraine the EEG changes are non-specific.

Creutzfeldt-Jakob disease is a neurodegenerative disorder caused by prion disease which presents clinically with dementia and myoclonic jerks (often elicited by startle). The EEG contains periodic repetitive discharges, typically at a rate of 1-2/second, occurring bilaterally. This feature, while not always present early in the illness, is strongly suggestive of the diagnosis.

Huntington's chorea shows a generalized flattening of the EEG trace that is thought to be due to loss of basal ganglia cells.

Alzheimer's dementia is characterized by reduced alpha activity on EEG.

Delirium usually shows slow alpha activity and increased delta activity on EEG.

Herpes simplex encephalitis is characterized by discharges occurring every 1-3 seconds with slow-wave activity prominent in the temporal areas. These abnormalities on the EEG typically occur within the first 2 weeks of illness.

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Great work with all your posts, many thanks.

A few more...

D.T. - generally faster ryhthms, or Normal

Space Occupying lesion - localised slower waves over area of lesion

Pick's often Normal

Triphasic shrap waves in CJD, but not nvCJD, iatrogenic, or Gerstmann-Straussler-Scheinker

Drugs:

Antidepressants increase delta

Antipsychotics decrease beta and increase delta/theta

Anxiolytics increase beta and theta, decrease alpha

Lithium has minimal effects at therapeutic dose, but increased delta and theta in overdose.

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