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Gurpal

Feedback on the Part 2 ISQ/EMI papers autumn 2006

56 posts in this topic

After the Part II ISQ/EMI papers, please post an account of your experience, good or bad. If you remember any questions, please post them, even if you think you're repeating someone else's post. Thanks and good luck on results day!

;)

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Glad the ordeal is now over. I hope you all survived the long day!

I'll post a few questions as I remember them.

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OK, let's post a few questions. They're probably not as they were written in the exam, but just to get an idea...

- Memantine is a NMDA agonist.

- According to the receptor profile of Clozapine, it should cause less hypotension than other antipsychotics.

- Reboxetine is a pre-synaptic alpha-2 antagonist

- Atomoxetine is a Noradrenaline reuptake inhibitor

- People with Aspergers have usually an IQ below 70

- 80% of chlidren with autism will have an IQ below 70.

- 50% of dementias in old age are Lewy Body

- Giving up smoking decreases the efficacy of Clozapine.

- According to the CATIE study, the metabolic syndrome is exagerated in Olanzapine, compared to other atypical antipsychotics

- 60% of children with learning disabilities have Pica

- Pica responds well to antipsychotic medication

- Diminished responsibility is a concept that originates from the McNaughten rules

- Late stages of CJD may show a normal CT

- Alzheimer's disease can present with normal CT at postmortem (?)

- 5-HT3 effects its action through an ion gated receptor

- Men who abuse alcohol are more likely than women who abuse alcohol to develop Wernicke's encephalopathy.

- In adopted subjects who develop schizophrenia, biological parents are more likely to have a personality disorder than the adoptive parents

- Hypersalivation with Clozapine is caused by interaction with Muscarinic (anticholinergic) M3 receptors

- Lamotrigine is better than Lithium in the prevention of Depression in Bipolar Affective Disorder

- In Bipolar Disorder, depressive episodes become more frequent as the illness progresses

- In ADHD, behavioural + pharmacological treatment is more effective than pharmacological treatment alone

- Open injury affecting the right parietal lobe can cause... (disinhibition?)

- Night terrors occur on phase 3 and 4 of non-REM sleep

- Specific reading difficulty in children is associated with specific writing difficulty

- The incidence of specific reading difficulties in children is 1%

- Fluoxetine increases plasma levels of Clozapine

- Naltrexone is an opioid antagonist

- Naltrexone is effective in the relapse prevention for alcohol dependence

- Acamprosate has a similar action to Glutamate

- Non-pharmacological treatments in dementia delay institutional care

- Most adults wtih severe Learning Disabilities are in institutional care

- 49/50 is the cut off between mild and moderate Learning Disabilities

- Melatonin is a naturally occurring (imidazole?) derivative.

- Suicide in the elderly is mainly due to suicide

- Studies suggest that response to ECT is long lasting

- Several studies have linked the MMR vaccine to autism

- MMR vaccine is contraindicated in children with autism

- A high frequency EEG is characteristic of Huntington's

- In Huntington's disease there is a similar recreased memory in all decades of life

- A pregnant mother can transmit Mumps to her unborn child, which will cause the child to develop learning disabilities

- ICD-10 has a wider definition of hyperactivity disorder than DSM-IV, which accounts for a higher diagnosis of this condition when using ICD-10.

- Oligoantigenic therapy has been proven to work in children suffereing from ADHD

- Shoplifting is more frequent in women than men

- Shoplifting is associated with OCD

- In girls with Turner's, when the X chromosome originates from the father, the incidence of autism is similar to boys of the same age

- Marfan's syndrome is associated with self-injurious behaviour

- Amenorrhoea is a known effect that accompanies Bulimia

- Studies show that antidepressants are more efficacious in severe than mild depression.

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A few more...

- 1/4 of elderly in-patients who suffer a mood disorder present with mania.

- Boys who shoplift are often experiencing a mental health problem (?)

- Truancy is often carried out in groups

- If one of the parents has a translocated chromosome, the child has a 50% chance to inherit it.

- Death of either parent in childhood is associated with psychiatric morbidity later life.

- Depression in the elderly is associated with (some gene or another that I can't remember).

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Few more that keep coming to mind...

- Face recognition of fear is mediated through the amygdala.

- Chromosome 22q is associated with an increase in the development of schizophrenia

- Vascular dementia is associated with Down's syndrome

- Rapid withdrawal of dexamphetamine can cause seizures

- Withdrawal of Diazepam can cause depression

- Visuospatial tests can differentiate pseudodementia from dementia

- Alcohol detox in the community should not happen unless the individual has already had a medically monitored detox (or something along those lines)

- The incidence of Ebstein's anomaly when a mother is being treated with Lithium during pregnancy, is 1 in 500.

- In myasthenia gravis, anxiety attacks are a known cause of death

- The interaction between Diazepam and alcohol can be explained through pharmacokynetics

- Painless parotiditis is associated with Bulimia

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Help!! I can't stop!!!

- In the long term Deliberate Self Harm, the association with life events decreases

- &quot:lol:ecision matrix' is more appropriately used during the Action stage

- The activation of 5-HT1 receptors increases the release of Prolactin

- According to Eysenck's theory, extroverts are more likely to respond to operative conditioning than introverts

- Most antipsychotics are metabolised through the P450 2D6 cytochrome system

- Treatment with Benzodiazepines soon after trauma can avoid the occurrence of PTSD

- Alzheimer's Dementia is a known complication of HIV infection

- HIV virus enters the brain through macrophages

- HIV virus enters the brain at a late stage of the infection

- The prevalence of Chronic Fatigue Syndrome in children is around 1%

- The Edinburgh Postnatal Depression Scale is administered to mothers in the postnatal period

- Maternity blues usually peaks towards the tenth day post-partum

- Post-partum psychosis is usually considered as part of bipolar disorder

- Feelings of aggression towards others is one of the questions of the CAGE questionnaire

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Somebody stop me!!

- Untreated depression in the elderly often leads to the experience of visual hallucinations

- Dental erosions are often seen in children with learning disabilities because of food regurgitation and rumination

- Up to 450ms is considered a normal QTc

- In organic amnesia the recency effect is preserved when learning a list of names

- Panic attacks happen more often in social phobia than (?)

- Depression is a common occurrence in Agoraphobia

- Multiple Sclerosis can present with elated mood

- The prevalence of Tourette's is about 1 in 2,000

- Encopresis may be linked to strict parenting

- The male/female ration in Asperger's is 4:1

- Fragile X is associated with a decline in cognitive functioning in the adolescence

- Proteome is the collection of proteins currently in a cell (?)

- In Angelman's syndrome the abnormal chromosome inherited by the child is of paternal origin

-Delusional disorder in the elderly usually preceeds dementia

- Urban birth is associated with Schizophrenia

- Studies suggest that high Expressed Emotion leads to a quicker relapse in schizophrenia

- Bipolar disorder is associated with increased lateral ventricles

- The limbic system includes the dentate gyrus

- The planum temporale is situated in the lateral inferior part of the Temporal lobe

- MetVal allele variation is involved in the susceptibility of cannabis users to develop schizophrenia

- Scheider's first rank symptoms are a good prognostic factor in schizophrenia

- Tardive dyskinesia may occur through activation of D3 receptors

- Caucasians have a higher probability to develop Alzheimer's Dementia

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OK, just one more and I'm off (I think I've gone over the century). I need some rest!

- In Smith-Lemli-Opitz syndrome, there is self-injurious behaviour by pulling out fingernails.

I've got some other half-baked questions in my head. If I can come up with some more, I'll try to post them tomorrow (or thereafter).

Good luck everybody!

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EMIS

Medication In CAMHS

ADHD (3)

Depression (1)

Sleep problems in 3year old(2)

Choices

Clonidine

Methyphenidate

Atomoxetine

Fluoxetine

Melatonin

Diazepam

Risperidone

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Genetics

About

Peneterence

Heretibility

Concordance

Haplotype

Questions

Tells about genetic variation of trait

To the extent a phenotype appears

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Statistics EMI

A difficult one similar to one which came in the past

ANCOVA

ANOVA

Chi Square Test

Man Whitney test

T test

Multiple regression

Discriminant Analysis

Paired t test

A big question about comparing presence of ASPD in people who have conduct disorder as children

IQ and Height given , correlated and have normal distribution

Very confusing questions

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EEG EMI

Clinical scenarious given which were basically

Depression

Alz Dementia

Fronto temporal dementia

Choices were

Normal EEG

Alpha wave 8hz

Occipital alpha waves

Frontal alpha waves

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EMI

OCD and Depression

Fluoxetine

Sertraline

Desimipramine

Risperidone

Quetiapine

Lithium

Lamotrigine

Reboxetine

1)

A child of 13 with 5year old OCD has been depressed for 6months(1)

2)

Adult 25year old has OCD , which two AntiDepressents not helpfull

3)

A person has not responded to first line medication is having OCD which two medications you can use

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Side Effects of medication

NMS

Lithium intoxication

Diabetes Inspidus

Hypothyroidism

Pulmonary Embolism

Cardiomyopathy

Serotonin syndrome

1)

A person who has been on clozapine develops breathlessness,fatigue and palpitations

2)

A person using lithium for a long time develops Dehyration,raised sodium level,increased urination

3)

A person started on risperidone has NMS

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After the Part II ISQ/EMI papers, please post an account of your experience, good or bad. If you remember any questions, please post them, even if you think you're repeating someone else's post. Thanks and good luck on results day!

;)

hi guys,

found the critical review much harder than last time,essay choices were ok,basic science mcq bloody awful,clinical mcq not as bad s basic science and clinical emi's reasonabe

unfortunately missed out on the clinic in may so pretty frustrating to have to face the writtens again.

i feel all my hard work-esp for the mcq's was a waste of time as v little seemed familiar. i used the manchester notes,royal college mcq book and of course the superego cafe ;) but find i'm completely unprepared for the exam mcq's. and have to wildly guess most of them.

where do they get their questions from?? :-?

i wonder do other faculties have similarly unreasonable?

please let me know what u think

regards

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it was a tough day.

emi-

1.methylphenidate

2.clonidine

3.atomexitine

4.resperidone

5.diazepam

6.fluoxetine

7.melatonin

A.an agressive 8 yr old boy who has been unruly,impulsive and hyperactive(3 choices)

B.a 3 yr mild L.D. who is intolerable sleeping problem(2 choices)

C.a 12 yr old boy with severe depression(1 choice)

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Help me out guys!! :-/

Genetic EMI:

Peneterence

Heretibility

Concordance

Haplotype

gentic association

genetic linkage

somethin with a fraction??

linkage dysequilibrium??

Questions

disease caused mutation leading to phenotype

phenotype without dna sequence

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Right. These are already fading in my mind...

Atomoxetine is a noradrenaline reuptake inhibitor.

Schizoaffective disorder is a 'Mixed State' according to Kraepelin.

Fluoxetine raises clozapine levels.

Ejaculation in men is associated with paroxysmal headache!!!!!! :o

Children with disrupted attachments can reform them if placed with a family which is nurturilng of these attachments.

Encopressis is associated with over-involved families.

Fighting with peers is a likely presenting complaint from a gentle, over-involved, over-anxious family about their child.

Nope, I'm done. Off to sleep. At least its over!

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EMI

Demetia

Three clinical scenarious given which were

Alz Dementia (Late onset)

Lewy Body

Picks disease

Choices

Medial Temporal lobe atrpohy

Apo E

Tau gene

Sesitive to neuroleptics

Intracytoplasmic inclusion bodies

A few more

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god oreta....how do you manage to remember all that? i couldnt remember the 1st question by the time id reached the end of the paper! i think basic sciences was bad as usual. very few 'science' questions. lots of social stuff, nobody could know the answer to.

clinical paper was not bad, but most of the questions that got repeated, were worded differently, changing the whole meaning. its important how we word the isq's when we post them.

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All your posts are truly amazing particularly the memory capacity of oreta. do I stand a chance having done an exam with him?

well, I must say welldone to you all.

i remember an emi half haphazardly: (please feel free to complete it if you can)

with respect to prescribing in children:

atomoxetine

melatonin

fluoxetine

clonidine

diazepam

escitalopram

citalopram

risperidone

haloperidol

a 3yr old child was brought in by both parents, suffering with severe restlessness and intractable sleep, not responded to behavioural and psychological therapy. how would you treat? choose two of the above.

an 8year old is brought in with hx of social disruption restlessness reported by teachers (suggestive of ADHD anyway)

A 6yr old with poor social, communication and marked behavioural difficulties (suggestive of autism)

well i hope i have not mixed them up?

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All your posts are truly amazing particularly the memory capacity of oreta. do I stand a chance having done an exam with him?

well, I must say welldone to you all.

i remember an emi half haphazardly: (please feel free to complete it if you can)

with respect to prescribing in children:

atomoxetine

melatonin

fluoxetine

clonidine

diazepam

escitalopram

citalopram

risperidone

haloperidol

a 3yr old child was brought in by both parents, suffering with severe restlessness and intractable sleep, not responded to behavioural and psychological therapy. how would you treat? choose two of the above.

an 8year old is brought in with hx of social disruption restlessness reported by teachers (suggestive of ADHD anyway)

A 6yr old with poor social, communication and marked behavioural difficulties (suggestive of autism)

well i hope i have not mixed them up?

Thank you funky. Remembering all those questions doesn't mean I answered them right though...

Your EMI sounds about right. The only two things to say: I don't think Haloperidol was on the list, but Methylphenidate and Sertraline were.

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