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Gurpal

Part II ISQ Club - Drug Misuse

34 posts in this topic

20 Part II ISQs on two topics will be posted twice a week. You are encouraged to post a reply in the thread, stating whether you think an ISQ is true or false and why (eg. a short explanation, with reference to the textbook you used). Please only deal with one ISQ in each post and include the question as the first line of your post. All ISQs are taken from previous posts by Forum members.

In a few days this ISQ Club thread will be moved to the Question Bank board. If you submit an answer, your status will be changed to 'Question Bank member' and you will be able to see the Question Bank board. Please allow up to 48 hours for this change to happen.

1. Amphetamine causes physical dependence

2. Amphetamine abuse causes macrocytosis

3. LSD is associated with a withdrawal delirium

4. MDMA causes physical dependence

5. Butane abuse can cause visual hallucinations

6. Visual hallucinations are a recognised feature of cannabis use

7. Cocaine use can cause a psychosis lasting up to 4 weeks

8. Lofexidine is an opiate antagonist

9. Khat can cause a mania-like picture

10. Of IV heroin users, 50% die at 10 years

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Q 3) FALSE

DEPENDENCE DOES DEVELOP WITH LSD & HENCE NO WITHDRAWL REACTIONS SEEN.

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OOPS , IT SHOULD HAVE READ DEPENDENCE DOES NOT DEVELOP...............HENCE NO WITHDRAWL TO LSD ;)

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1) true:amphetamines cause physical dependence

(shorter oxford pg 573)

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q 45 in old age psychiatry:prominent cortical atrophy in wilsons disease:true

pg 392 core psychiatry

(someone had posted the answer to be false)

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2 false

complications include :'(

cardiovascular—hypertension, arrhythmias, myocardial infarction, cerebrovascular accident

obstetric—premature labour, placental abruption

psychiatric—anxiety, depression, aggressive behaviours, psychosis.(oxfd txtbk of psychiatry)

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??? 9 true ?Khat is primarily a social drug and its mild stimulant effects appear to promote social interaction. Users report loquacity, disinhibition, and improved concentration. Use is associated with anorexia and reduced need for sleep. (ox txtbk of psy)

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7) True

More prolonged use of high doses of cocaine can result in a paranoid psychosis with violent behaviour. This state is usually short-lived but may be more enduring in those with a pre-existing vulerability to psychotic disorder (Strang 1993)

Shorter Oxford Textbook of Psychiatry p574-575

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4.MDMA causes physical dependence

False

It does not cause withdrawal efects.

Just be aware that in the College Seminars it says:

It rapidly produces tolerance but is unlikely to induce dependence. However, it has a limited dependence-inducing potential which seems to be realted to the fact that there is a much reduced effect with repeated use and a need for significant gaps between episodes of use if the full subjective effects are to be experienced.

I think the exact wording of the ISQ would be the important one in realtion to a question on MDMA.

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5. Butane abuse can cause visual hallucinations

True

Larger dose or prolonged use may lead to ataxia, tinnitus, visual and auditory hallucinations or confusion.

ref college seminars p 51

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2- Amphetamin abuse causes macrocytosis.

True. due to folic acid defficiency.

sorry about the reference.

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1. False - physical dependence is rare in amphetamine use but psychological dependence develops in regular users.

Guildford course

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2. False - I could find no mention of amphetamine causing macrocytosis.

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3. False - LSD is not associated with a withdrawal delirium. In acute use it causes hallucinations in all modalities which can vary from pleasant to unpleasant. It does not cause dependence.

Guildford Course

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5. True - solvents cause intense intoxication, loss of balance, auditory and visual hallucinations.

Guildford Course

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6. True - visual hallucinations are a recognised effect of cannabis use, though rare.  Cannabis causes light intoxication, silliness, giggles, 'munchies', increased appetite.

Guildford Course

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7. True - cocaine can cause a psychosis lasting 4 weeks.

Guildford Course

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8. False - Lofexidine is an a2-agonist which reduces NA-related symptoms.

Fundamentals of Clinical Psychopharmacology (p.99)

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10. False - at 7-year follow-up (Stimson et al, 1978) 12% of IV heroin users are dead.

Guildford Course

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