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Part II ISQ Club - Psychosis

24 posts in this topic

Part II ISQ Club - Psychosis

20 Part II ISQs on two topics will be posted twice a week. You are encouraged to post a reply in the thread, stating whether you think an ISQ is true or false and why (eg. a short explanation, with reference to the textbook you used). Please only deal with one ISQ in each post. All ISQs are taken from previous posts by Forum members.

In a few days this ISQ Club thread will be moved to the Question Bank board. If you submit an answer, your status will be changed to 'Question Bank member' and you will be able to see the Question Bank board. Please allow up to 48 hours for this change to happen.

1 Late onset schizophrenia is commoner in women than men

2 Kraeplin described oneirophrenia as a mixed state

3 Nicotine decreases the levels of antipsychotics

4 Delusional disorder is associated with passivity phenomena

5 Delusional disorder in later life is associated with subfertility

6 Perceptual disturbances are seen in derealisation

7 Delusion of misidentification is associated with impaired facial recognition memory

8 Clozapine can be safely combined with carbamazepine

9 Clozapine acts on D3 and D4 receptors.

10 Cigarette smoking increases the level of antipsychotics

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hi .i wasn't sure.is it one ans per reply.anyway

late onset schizophrniais commoner in women than men-true(oxford) :)

bharti

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Clozapine should not be combined with carbamezapine- higher chances of agranulocytosis ( both are bone marrow suppresants)

smoking decreases the levels of antipsychotics

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Clozapine acts on D3 and D4 receptors-TRUE

Use of drugs in Psychiatry Gaskell .Clozapine blocks all types of dopamine receptors D1-5

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7 Delusion of misidentification is associated with impaired facial recognition memory

TRUE The right hemisphere, which has a recognised role in facial processing may be preferentially affected ... OTP Edelstyn and Oyebode 1999

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1 Late onset schizophrenia is commoner in women than men

TRUE A consistent finding is an excess of females over males in a ratio of 7:1 ..... OTP

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2 Kraeplin described oneirophrenia as a mixed state

FALSE

oneirophrenia - Meduna's term for a form of schizophrenia characterized by disturbances of the sensorium (illusions, confusions, disorientation), amnesia, stupor, and hallucinations.

from the medical dictionary

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1. true. 14% in women and 4% in men over the age of 65( bird &harrison page 199 - 2nd edition)

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q 6 Perceptual disturbances are seen in derealisation

True

ref Sims 2003 p. 95

'Perception is accompanied by affect, which may be a feeling of familiarity,..of proximity....This is usually appropriate and so ignored.However, changes in these feelings may present as symptoms, for example, 'everything looks clear but it all looks miles away' ...... these and many other feelings are described under derealisation.'

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10 false.cigarette smoking shown to reduce levels of haloperidol + clozapine.Also reduces t1/2 of olanzapine by 21% (maudesley antipsychotic review)

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1005 sure as follows,

2f 3t 6t 8f 9t 10f as per oxford and Harrison

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Delusional disorder in later life is associated with subfertility

ANS- T- delusional disorders are associated with low fecundity (puri & hall)

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how about question no-4.why would del disorder cause passivity?? :-/

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1) T

LOS patients show a female predominance not found among EOS cases . Most studies of LOS show a 2-10 times higher proportion of women than men. In a review by Pearlson and Rabins (52), the authors concluded that there seemed to be an age-related fall in the number of dopamine D2 receptors but men lost them at a faster rate with increasing age, leaving older women with a relative excess. It has also been suggested that estrogen in premenopausal women might have a protective role. The contribution of these and other factors to the later onset of schizophrenia in women is unclear.

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4. Delusional disorder is associated with passivity phenomena              

False

Key feature of delusional disorder is “non-bizarre delusions in the absence of any other symptoms of schizophrenia” (Page 515, Synopsis of Psychiatry, Kaplan & Sadock, 8th Ed)

“… no history of schizophrenic symptoms (delusions of control, thought broadcasting, etc.” (ICD-10)

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5 Delusional disorder in later life is associated with subfertility

true

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Clozapine should not be combined with carbamezapine- higher chances of agranulocytosis ( both are bone marrow suppresants)

smoking decreases the levels of antipsychotics

carbamazepine and clozapine shd not be combined for obvious reasons.if an antiepileptic is needed,valproate is the drug of choice for those on clozapine.

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6 Perceptual disturbances are seen in derealisation

true

perceptual disturbances are commom in both depersonalization and derealization.also,they occur together, and....they are real and unreal.

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