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katybriffa

question on forest plot; paper 3

4 posts in this topic

hi there,

sorry to post this question here, nobody seems to read the critical app. section on this board. I was wondering if anyone remember the questions that were asked on the forest plot in the paper. I vaguely remember it being a meta-analysis of RCTs in the use of clozapine.  

There were 3-4 questions that followed the example. I would appreciate it if someone can post those quest. and we can discuss them here.

ta.

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just to help with the question, i managed to dig up a good article on forest plots and how to make sense of them on the internet. the link is

www.psychiatry.univr.it/page_eps/docs/2006_4_Cipriani.pdf

ta.

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Here u go,collected from previous thread

http://bjp.rcpsych.org/cgi/content/full/183/2/161/FIG1

A forest plot about different studies about clozapine.

Studies with minus (-) sign were in favour of clozapine (8 studies)

Studies with plus (+) sign were against clozapine (1 study)

Question 1.

How many studies  were in favour of clozapine

1. 8

2. 6

3. 5

4. 4

5. 1

Question 2.

Which 2 of these studies were statistically most significant

1. Kenneth 8's study and Johnson's study

2. Kenneth 8's study and Marshall's study

3. McKenzie's study and Marshall's study

4. O' Neill's study and Simpson's study

Question 3.

Which of the following statement is correct.

1. Effect size of Kenneth 8's study was larger than Simpson's study

2. Effect size of Simpson's study was larger than Kenneth 8's study

3. Confidence interval for Kenneth's study were extremely broad

4. Confidence intervals for Simpson's study are clinically insignificant as they cross the line of unity

5. There was significant heterogeneity

       

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